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Sunlight and vitiligo |
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Light is made
up of energy bunches, known as photons, moving in space as electromagnetic
waves (or radiation), whose length determines the quantity of photons
that can be used by the body: the positive biological effect of
radiation thus only depends on its wavelength. According to a classification
based on wavelengths, sunlight is made up (Fig.
10) of ultraviolet rays (UV), visible rays (violet, indigo,
blue, green, yellow, orange, red), and infrared rays (IR). Ultraviolet
(UV) rays are responsible for the greatest benefits of light; based
on wave frequency in nanometres (nm), they include in turn UVC rays
(200-260 nm), UVB rays (261-310 nm), and UVA rays (311-400 nm).
The hyperpigmenting action of sunlight has been known for a very
long time: tanning is obtained through exposure to the intense natural
light of summer months or of the Tropics. However sunlight has no
impact on vitiligo, because melanin production in melanocytes is
only restored by UVB rays, which are contained in sunlight in very
small quantities (0,2% and as little as 0,02% in industrialised
regions). Such quantities, however, may perform a positive supporting
role, provided that exposure to sunlight occurs after a number of
RatokŪtherapy
sessions. IR and UVC rays are not significant for the treatment
of vitiligo. UVA rays, accounting for 4,8% of sunlight, cause a
quick but transitional tanning of the normally pigmented skin by
increasing the quantity of the existing melanin; on the other hand
they do not affect melanocytes and are therefore unable to promote
the production of new melanin required for repigmentation of vitiligo
patches. In addition, UVA rays may reach the second skin layer,
the dermis, thus causing a light-related skin damage known as photoaging. |
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